Macmiror complex

McMiror complex is indicated for local use in gynecology.

It has an antibacterial, antifungal, antiprotozoal effect (affects the protozoa - Toxoplasma, trypanosomes, pneumocystas, Giardia, amoeba, Trichomonas, Leishmania).

The active ingredients of the complex are nifuratel (a nitrofuran derivative), which is active against fungi, protozoa, bacteria and nystatin, an antibiotic with antifungal activity, especially effective against Candida albicans.

Clinical and pharmacological group

A drug with antibacterial, antiprotozoal and antifungal effects for local use in gynecology.

Pharmacy sales terms

It is released on prescription.


How much is Makmiror? The average price in pharmacies is 750 rubles.

Release form and composition

"McMiror complex" candles consist of:

  • Nifuratela (500 mg in one suppository)
  • Nystatin
  • Auxiliary substances.

The "McMiror Complex" candles are available in blisters of two options:

  • 8 suppositories in one
  • 12 suppositories in one.

Packaging made of cardboard contains 1 blister. Candles have an oval shape, yellow-brown color. In the middle of the suppository there is an oily liquid with a yellow tinge. The suppository itself is soft to the touch (gelatinous consistency).

Pharmacological effect

McMiror complex is a combined drug for local use in the treatment of gynecological diseases. Pharmacological properties of the drug due to the action of its active ingredients. The main active ingredients of the drug are nystatin and nifuratel.

Nystatin is a mycostatic antimicrobial agent, the action of which is aimed at destroying the cells of the fungus (joining the sterols in the membrane of fungal cells, it disrupts their structure, destroying the cell itself). Nystatin is highly active against Candida fungi. With complex use with nifuratel, a powerful, pronounced antimycotic effect is provided.

The drug has antifungal, antibacterial and antiprotozoal effects (shows activity to the simplest - trypanosomes, toxoplasma, pneumocystis, amoebae, lamblia, trichomonads). Due to such diverse effects, this drug is used in the treatment of a wide variety of vaginal infections.

Indications for use

Macmiror complex is prescribed for the treatment of vaginal infections triggered by susceptible microorganisms: vaginal candidiasis, urogenital trichomoniasis, bacterial infections developing in the urogenital area.

Good reviews about the McMiror complex used in the local treatment of chlamydial infections.


The drug can be used only on prescription. Before using suppositories, patients should carefully read the enclosed instructions. The main contraindication is individual intolerance to the components contained in the preparation.

Relative contraindications for use are pregnancy in the first trimester and up to 18 years of age due to lack of experience with adolescents.

Use during pregnancy and lactation

This antibiotic can be prescribed to pregnant women only by a doctor according to strict indications. This takes into account the potential risk to the fetus, because the main component is able to penetrate through the placenta nifuratel.

If it becomes necessary to use the drug during lactation, then at the time of admission the woman should stop feeding (the main active ingredient passes into breast milk).

Dosage and method of use

The instructions for use indicate that in order to achieve maximum effect, the suppository is inserted deep into the vagina.

  • Intravaginal: 1 vaginal suppository is administered daily in the evening before bedtime for 8 days or in accordance with the recommendations of the doctor.

During menstruation, the use of suppositories is not recommended, since the therapeutic effect will be significantly reduced. If a woman knows that her menstruation should begin the other day, then it is better to postpone the course of treatment until the end of critical days.

Side effects

Makmiror complex is usually tolerated well, only in rare cases allergic manifestations occur in the form of a rash, itching on the skin.


Since the absorption of the drug Makmiror Complex is very low and the drug acts locally, the probability of an overdose is negligible. The uncontrolled use of suppositories is not recommended, since the above-described side effects may occur against this background.

Special instructions

It is necessary to conduct simultaneous treatment of the sexual partner because of the danger of re-infection. During the period of drug treatment should avoid sexual contact.

Suppositories are not used for treatment in children, if necessary, use of the drug in this category of patients, it is recommended to use the drug McMiror Complex in the dosage form vaginal cream complete with applicator (graduated syringe). The presence of a special nozzle allows you to enter the cream without damaging the hymen.

Drug interactions

The clinically significant interaction of McMiror Complex with other drugs has not been established.


We picked up some reviews of people using the drug McMiror:

  1. Helena. My gynecologist assigned me a macmorir complex after cauterization of cervical erosion. The recovery period went well, without inflammation and pain. Except for one thing, we’ve got tired of discharge all day long from these candles.
  2. Tatyana. Candles are good, but flow well and stain the linen. For me, so every day is not enough, put the pads on three drops.
  3. Galina. My daughter often had abdominal pain, mainly in the area of ​​the liver. After the examination, she was diagnosed with giardiasis. The doctor prescribed the drug Makmimor 200 mg tablets in a course of 10 days. Additionally, milk thistle was prescribed as a choleretic agent. The treatment was effective, control tests did not reveal parasites.


Structural analogues of the active substance of the drug McMiror has not.

Before using analogues consult your doctor.

Storage conditions and shelf life

It is recommended to keep the medicine away from children, avoiding heating of the package and direct sunlight. Maximum storage temperature should not exceed 25 degrees.

The shelf life of the suppositories is indicated on the package and is 3 years from the date of manufacture.

Watch the video: MACMIROR (April 2020).


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